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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
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Adult Stem Cells01:33

Adult Stem Cells

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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
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Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

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Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
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Stem Cell Culture01:17

Stem Cell Culture

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Embryonic Stem Cells00:57

Embryonic Stem Cells

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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
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iPS Cell Differentiation01:22

iPS Cell Differentiation

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The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
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Updated: Jul 15, 2025

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
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Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

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Stem cell therapy for erectile dysfunction: a systematic review.

Thiago P Furtado1, Gal Saffati2, Marcelo H Furtado3

  • 1Faculdade de Ciencias Medicas de Minas Gerais, Belo Horizonte, 30130-110, Brazil.

Sexual Medicine Reviews
|September 27, 2023
PubMed
Summary
This summary is machine-generated.

Stem cell (SC) therapy shows promise for treating erectile dysfunction (ED) by addressing underlying causes. While safe, a lack of standardized methods hinders comparative analysis of current trials.

Keywords:
erectile dysfunctionintracavernosal injectionneurogenicregenerative therapystem cellsvasculogenic

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Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents
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Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents
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Area of Science:

  • Regenerative Medicine
  • Urology
  • Cell Biology

Background:

  • Erectile dysfunction (ED) significantly impacts men's quality of life, with current treatments offering symptomatic relief rather than addressing root causes.
  • Stem cells (SCs) present a novel therapeutic avenue for ED due to their inherent anti-inflammatory and regenerative properties.

Approach:

  • A systematic review was conducted, analyzing clinical trials published up to March 2023 across six electronic databases.
  • Inclusion criteria focused on human clinical trials evaluating SC therapy for ED, excluding non-human studies, reviews, and case reports.
  • Data extraction concentrated on safety, efficacy, and erectile outcomes from 18 selected studies involving 373 patients.

Key Points:

  • Multiple SC types were investigated, including mesenchymal stem cells, adipose-derived stem cells, and bone marrow-derived stem cells.
  • SC therapy demonstrated potential as a safe and innovative treatment for organic ED.
  • Various SC sources were explored, including mesenchymal stem cells, adipose-derived stem cells, and bone marrow-derived stem cells.

Conclusions:

  • Stem cell therapy holds significant promise for treating organic erectile dysfunction.
  • Standardization of techniques and the implementation of controlled groups are crucial for robust evaluation and comparison of future SC trials in ED treatment.