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Updated: Jul 15, 2025

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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Toxic leukoencephalopathy versus delayed post-hypoxic leukoencephalopathy after oral morphine sulphate overdose

Nicholas P Rossi1, Goutham Sathyanarayanan2, MdSakir Mahmood2

  • 1Acute Medicine, University Hospitals of Morecambe Bay NHS Foundation Trust, Lancaster, Lancashire, UK nprossi2@gmail.com.

BMJ Case Reports
|September 27, 2023
PubMed
Summary

Oral morphine overdose can cause toxic leukoencephalopathy (TLE), a rare brain condition. This case highlights the diagnostic challenges in differentiating opioid-induced TLE from other neurological injuries.

Keywords:
Drugs misuse (including addiction)NeuroimagingPathologyRadiology

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