Related Experiment Video
Updated: Jul 15, 2025

Endotracheal Intubation via Tracheotomy and Subsequent Thoracotomy in Rats for Non-Survival Applications
Published on: March 15, 2024
Tracheostomy in Severe Bronchopulmonary Dysplasia-How to Decide in the Absence of Evidence
Audrey N Miller1, Edward G Shepherd1, Amy Manning2
1Comprehensive Center for Bronchopulmonary Dysplasia, Department of Pediatrics, Division of Neonatology, Nationwide Children's Hospital, Ohio State University College of Medicine, Columbus, OH 43205, USA.
Insights
Tracheostomy may be necessary for infants with severe bronchopulmonary dysplasia (BPD) to survive and transition home. However, optimal timing and indications for this life-saving procedure remain unclear, leading to varied clinical practices.
Area of Science:
- Neonatal Medicine
- Pediatric Surgery
- Respiratory Medicine
Background:
- Severe bronchopulmonary dysplasia (BPD) often necessitates long-term invasive ventilation.
- Tracheostomy, while life-saving for infants with severe BPD, carries significant risks including mortality, complications, and caregiver burden.
- Current practices for tracheostomy in infants with severe BPD lack standardization due to unknown indications and optimal timing.
Purpose of the Study:
- To address the critical knowledge gap regarding the specific indications and timing for tracheostomy in infants with severe BPD.
- To explore the complex decision-making process for tracheostomy in this vulnerable population.
- To highlight the need for evidence-based guidelines to improve patient outcomes and reduce practice variations.
Main Methods:
- This study reviews existing literature and clinical data on tracheostomy in infants with severe BPD.
- Analysis of factors influencing tracheostomy decisions and associated outcomes.
- Discussion of current practice variations across different clinical centers.
Main Results:
- The precise indications and optimal timing for tracheostomy in severe BPD remain undefined.
- Significant variability exists in clinical approaches to tracheostomy for these infants.
- The decision for tracheostomy involves balancing survival benefits against substantial risks and caregiver impact.
Conclusions:
- Establishing clear indications and timing for tracheostomy in severe BPD is crucial for optimizing infant outcomes.
- Standardized approaches are needed to facilitate evidence-based practice and improve care.
- Further research is essential to guide clinical decision-making and reduce practice disparities.
Abstract:
Infants with the most severe forms of bronchopulmonary dysplasia (BPD) may require long-term invasive positive pressure ventilation for survival, therefore necessitating tracheostomy. Although life-saving, tracheostomy has also been associated with high mortality, postoperative complications, high readmission rates, neurodevelopmental impairment, and significant caregiver burden, making it a highly complex and challenging decision. However, for some infants tracheostomy may be necessary for survival and the only way to facilitate a timely and safe transition home. The specific indications for tracheostomy and the timing of the procedure in infants with severe BPD are currently unknown. Hence, centers and clinicians display broad variations in practice with regard to tracheostomy, which presents barriers to designing evidence-generating studies and establishing a consensus approach. As the incidence of severe BPD continues to rise, the question remains, how do we decide on tracheostomy to provide optimal outcomes for these patients?
Related Concept Videos
Tracheostomy Decannulation
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
Oxygen Delivering System III: Tracheostomy and T-piece
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
Tracheostomy Care I: Pre-procedural Steps
Required Equipment
The equipment necessary for tracheostomy care includes:
Tracheostomy: Procedure and Tubes
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
Trachea
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
Tracheostomy Care II: Procedure
Step 1: Perform hand hygiene, and put on personal protective equipment: gown, gloves, mask...

