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Automated Diagnosis for Colon Cancer Diseases Using Stacking Transformer Models and Explainable Artificial

Lubna Abdelkareim Gabralla1, Ali Mohamed Hussien2, Abdulaziz AlMohimeed3

  • 1Department of Computer Science and Information Technology, Applied College, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.

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|September 28, 2023
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Summary
This summary is machine-generated.

A new deep learning model accurately predicts colon cancer by stacking convolutional neural network (CNN) models. This advanced technique improves early detection and treatment outcomes for this common disease.

Keywords:
CNNcolon cancerexplainable AI (XAI)stacking ensembletransfer learning

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Area of Science:

  • Oncology
  • Computer Science
  • Artificial Intelligence

Background:

  • Colon cancer is a leading global cancer, with nearly two million cases in 2020.
  • Accurate early detection is crucial for successful colon cancer treatment.
  • Deep learning offers potential for enhanced diagnostic accuracy in medical imaging.

Purpose of the Study:

  • To propose a novel heterogenic stacking deep learning model for colon cancer prediction.
  • To improve the performance of colon cancer detection using integrated deep learning approaches.
  • To evaluate the proposed model against established deep learning architectures.

Main Methods:

  • Developed a heterogenic stacking deep learning model integrating pretrained convolutional neural network (CNN) models.
  • Utilized a metalearner to enhance prediction performance within the stacking framework.
  • Evaluated the model on the LC25000 and WCE colon cancer image datasets (binary and multiclassified).
  • Compared performance against VGG16, InceptionV3, Resnet50, and DenseNet121 using accuracy, recall, precision, and F1 score.

Main Results:

  • The proposed stacking deep learning model achieved superior performance on both datasets.
  • For LC25000, the stacked model attained 100% accuracy, recall, precision, and F1 score.
  • For WCE, the stacked model achieved 98% accuracy, recall, precision, and F1 score.
  • Stacking-SVM demonstrated higher performance than individual models like VGG16, InceptionV3, Resnet50, and DenseNet121.

Conclusions:

  • Heterogenic stacking deep learning models significantly enhance colon cancer prediction accuracy.
  • The proposed stacking approach offers a robust and highly effective method for colon cancer detection.
  • Explainable AI (XAI) methods can be applied to understand black-box deep learning models in this context.