Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

4.0K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
4.0K
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

1.6K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
1.6K
Classification of Epithelial Tissues: Overview01:22

Classification of Epithelial Tissues: Overview

13.5K
Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
Based on the number of cell layers,...
13.5K
Tumor Immunotherapy01:27

Tumor Immunotherapy

551
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
551
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

2.8K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.8K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

4.7K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Case of Kaposi Sarcoma Misdiagnosed for 2 years: A Case Report.

Case reports in medicine·2025
Same journal

Correction: Luca et al. Global and Regional Diagnostic Results of Progress Toward Cervical Cancer Elimination, According to the WHO Strategy: A Systematic Literature Review with Narrative Synthesis. <i>Diagnostics</i> 2026, <i>16</i>, 1224.

Diagnostics (Basel, Switzerland)·2026
Same journal

Association Between Systemic Inflammatory Response Biomarkers and Disease Activity in Systemic Lupus Erythematosus: A Multi-Center Retrospective Study.

Diagnostics (Basel, Switzerland)·2026
Same journal

Vertebrogenic Low Back Pain and Basivertebral Nerve Ablation: A Review of Mechanisms, Imaging-Driven Selection, and Clinical Outcomes.

Diagnostics (Basel, Switzerland)·2026
Same journal

Multivalvular Carcinoid Heart Disease: The Role of Echocardiography in Diagnosis and Selection for Heterotopic Bicaval Valve Implantation.

Diagnostics (Basel, Switzerland)·2026
Same journal

Data-Efficient and Explainable Multimodal Survival Prediction in NSCLC Using Deep Image Embeddings, Clinical Variables, and Gradient-Boosted Trees.

Diagnostics (Basel, Switzerland)·2026
Same journal

Anomalous Left Coronary Artery from the Pulmonary Artery: Cinematic Volume Rendering Technique for Enhanced Anatomic Visualization.

Diagnostics (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: Jul 15, 2025

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
07:01

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

Published on: April 17, 2013

21.1K

Thymoma: An Overview.

Doaa Alqaidy1

  • 1Department of Pathology, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

Diagnostics (Basel, Switzerland)
|September 28, 2023
PubMed
Summary
This summary is machine-generated.

Thymomas, common anterior mediastinal tumors, present diagnostic challenges in classification and staging. This review explores histopathology evaluation, clinical features, and current management strategies for these rare neoplasms.

Keywords:
classificationmediastinumstagingthymomathymus

More Related Videos

Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

1.7K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

560

Related Experiment Videos

Last Updated: Jul 15, 2025

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
07:01

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

Published on: April 17, 2013

21.1K
Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

1.7K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

560

Area of Science:

  • Oncology
  • Pathology
  • Thoracic Surgery

Background:

  • Thymomas are the most common mediastinal epithelial tumors, typically found in the anterior mediastinum.
  • Their rarity leads to ongoing debate regarding nomenclature, classification, and staging among pathologists.
  • The clinical significance of histologic subtyping versus staging at diagnosis remains a point of contention.

Purpose of the Study:

  • To review challenges in the histopathologic evaluation and staging of thymomas.
  • To discuss the clinical characteristics of thymomas.
  • To provide an overview of current management strategies for thymomas.

Main Methods:

  • Review of existing literature on thymoma classification, staging, and clinical behavior.
  • Discussion of diagnostic challenges faced by surgical pathologists.
  • Synthesis of current knowledge on thymoma management.

Main Results:

  • Histopathologic classification and staging of thymomas present significant diagnostic challenges.
  • Debate persists regarding the relative importance of histologic subtypes versus staging in clinical outcomes.
  • Understanding these challenges is crucial for accurate diagnosis and treatment planning.

Conclusions:

  • Accurate histopathologic evaluation and staging are critical for effective thymoma management.
  • Further research and consensus are needed to refine thymoma classification and staging systems.
  • A comprehensive approach integrating pathology, clinical data, and management strategies is essential for improving patient outcomes.