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A Relation between Obstructive Sleep Apnea in Pregnancy and Delivering Small for Gestational Age Infant-A Systematic

Alicja Grajczyk1, Karolina Dżaman1, Katarzyna Czerwaty1

  • 1Department of Otolaryngology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland.

Journal of Clinical Medicine
|September 28, 2023
PubMed

Insights

Obstructive sleep apnea (OSA) in pregnancy may not significantly affect infant size, though some studies suggest a link. Early screening for OSA symptoms in pregnant women is recommended to mitigate potential risks.

Area of Science:

  • Obstetrics and Gynecology
  • Sleep Medicine
  • Perinatal Health

Background:

  • Obstructive sleep apnea (OSA) during pregnancy poses risks to maternal and infant well-being.
  • The association between maternal OSA and adverse infant outcomes, specifically small for gestational age (SGA) infants, requires further clarification.

Purpose of the Study:

  • To systematically review and synthesize evidence on the association between obstructive sleep apnea during pregnancy and the delivery of small for gestational age infants.

Main Methods:

  • A systematic literature search was conducted across MEDLINE (PubMed), Scopus, and Cochrane Library.
  • Studies were screened according to PRISMA 2020 guidelines, with 18 studies meeting the inclusion criteria after initial filtering of 744 articles.

Main Results:

  • The majority of included studies suggest that OSA during pregnancy may not have a significant impact on SGA.
  • However, a subset of studies indicated a potential relationship between OSA and SGA, highlighting inconsistent findings.

Conclusions:

  • While evidence is not definitive, screening pregnant women for OSA symptoms and performing sleep tests when indicated is advisable.
  • Early detection and management of OSA in pregnancy could potentially reduce adverse outcomes, but more research is needed for conclusive evidence.

Keywords:
birth weightobstructive sleep apneapregnancysleep hypopneasmall for gestational ageupper airway resistance

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