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Daily Duration of Compression Treatment in Chronic Venous Disease Patients: A Systematic Review
Sevara Mirakhmedova1, Amirkhan Amirkhanov1, Evgenii Seliverstov1
1Department of Surgery, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
Insights
This review found no reliable data to support specific daily compression therapy durations for chronic venous disease patients. More research is needed to establish optimal compression regimens for various clinical scenarios.
Area of Science:
- Vascular Medicine
- Medical Research Methodology
Background:
- Chronic venous disease (CVD) management lacks established guidelines for daily compression therapy duration.
- Optimal compression treatment regimens are not well-defined for patients with venous conditions.
Purpose of the Study:
- To systematically review and establish the optimal daily duration of compression treatment for patients with chronic venous disease.
- To identify evidence-based recommendations for compression therapy regimens.
Main Methods:
- A systematic search of CENTRAL and MEDLINE databases was conducted.
- Included studies comprised RCTs, non-RCTs, reviews, systematic reviews, meta-analyses, and guidelines on compression therapy for varicose veins.
- Study quality varied, precluding meta-analysis due to data heterogeneity.
Main Results:
- Thirty-two RCTs and other study designs reported on compression duration and regimens for various patient groups.
- Data were reported for post-invasive treatment, venous ulcer treatment, and venous symptoms.
- While duration varied by clinical scenario, no precise regimen data were found.
Conclusions:
- There is a lack of reliable data to support specific daily compression treatment regimens for different chronic venous disease patient cohorts.
- Further high-quality research is required to define optimal compression therapy protocols.
Abstract:
Background: There are no data on the daily regimen of compression therapy in patients with chronic venous disease. This systematic review aimed to establish the optimal daily duration of compression treatment. Methods: A systematic search of CENTRAL and MEDLINE was performed to identify RCTs, non-RCTs, reviews, systematic reviews, meta-analyses, and guidelines evaluating the use of compression regimens in the treatment of varicose veins. Results: Thirty-two RCTs, three non-RCTs, four observational studies, and two crossover trials reporting the duration and regimes of compression treatment fulfilled the inclusion criteria. The daily duration of compression was reported in patients after invasive treatment, for venous ulcer treatment, in patients with venous symptoms. The quality of the studies varied. We could not conduct a meta-analysis due to the heterogeneity of the research data and their quality. Twenty-three studies reported results of compression usage after invasive procedures. Eight studies reported daily duration regimens in patients with venous ulcers. Nine studies reported the impact of compression on venous symptoms and/or edema or limb volume change. One study was conducted to assess if compression improves QoL in venous patients. While there was a clear difference found in the daily duration depending on the clinical scenario, no data in support of exact regimens were found. Conclusions: There are no reliable data supporting exact daily regimens of compression treatment in various cohorts of CVD patients.
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