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Exploring Patient Beliefs and Medication Adherence in the Mediterranean Context: A Cross-Sectional Study in Patients
Vasiliki Belitsi1, Thomas Tsiampalis1,2, Matina Kouvari2,3
1Department of Nutrition and Dietetics, School of Physical Education, Sports and Dietetics, University of Thessaly, 42132 Trikala, Greece.
Insights
Poor adherence to vascular medications is common, affecting nearly half of patients. Addressing patient beliefs about treatment efficacy and alternatives is crucial for improving cardiovascular medication adherence in Greece.
Area of Science:
- Cardiology
- Public Health
- Behavioral Science
Background:
- Poor adherence to vascular medications is a significant contributor to cardiovascular disease (CVD) events and mortality.
- Understanding patient beliefs is key to improving treatment compliance.
Purpose of the Study:
- To examine patient beliefs and views influencing adherence to medical treatment for cardiovascular disease.
- Investigate factors affecting medication adherence in a multi-center study in Greece.
Main Methods:
- A multi-center study involving 1988 patients with cardiovascular disease or related disorders in Greece.
- Utilized the 4-item Morisky Medication Adherence Questionnaire to assess adherence and patient beliefs.
Main Results:
- Nearly half of the participants (48.8%) exhibited poor medication adherence.
- Negative beliefs about medication were strongly associated with non-adherence (OR = 2.73).
- Concerns regarding drug efficacy and preference for alternative therapies were significant factors in non-adherence.
Conclusions:
- Patient beliefs and views are critical targets for interventions to improve medication adherence.
- Tailored, context-sensitive strategies are needed to enhance adherence and health outcomes in the Mediterranean region.
- Cultural, socioeconomic, and clinical factors specific to the Mediterranean context should inform adherence interventions.
Background:
Evidence has shown that poor adherence to vascular medications contributes to a considerable proportion of all cardiovascular disease (CVD) events and mortality. The aim of the present work was to examine patients' beliefs/views that affect their level of adherence to the assigned medical treatment in the context of a multi-center study in Greece.
Methods:
Between July 2022 and April 2023, 1988 patients (1180 females) with established cardiovascular disease or relevant cardiometabolic disorders were chosen from seven medical centers in Greece. The 4-item Morisky Medication Adherence Questionnaire gauged medication adherence and investigated patients' beliefs/views regarding treatment.
Results:
Among participants, 51.2% showed perfect medication adherence, contrasting with 48.8% displaying poor adherence. Patients with negative medication beliefs were around three times more likely to be non-adherent (OR = 2.73; 95% CI = 2.28-3.28). Non-adherers held concerns about drug efficacy (OR = 2.34; 95% CI = 1.10-4.97) and favored alternative therapies (OR = 2.25; 95% CI = 1.75-2.91).
Conclusion:
The findings highlight the significance of addressing patient beliefs/views to improve medication adherence. The distinct Mediterranean context, influenced by cultural, socioeconomic, and clinical factors, emphasizes the need for tailored interventions. This underscores the call for contextually sensitive strategies to boost medication adherence and improve health outcomes in this unique region.
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