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Updated: Aug 10, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
[Pathogenesis of "diurnal" and "nocturnal" strokes]
Abstract:
A comprehensive clinico-physiological investigation involved 23 patients of whom 13 had had a "diurnal" and 10 a "nocturnal" cerebral stroke. The structure of the nocturnal sleep was studied by polygraphic recording; the authors also studied the circadian rhythm of the clotting properties of blood, pulse blood filling of the cerebral vessels and arterial pressure. It was found that the structure of dream in patients with a history of a "nocturnal" stroke was characterized by an increase in the activity of the mechanisms responsible for the phase of rapid sleep. Characteristic features of the circadian dynamics of the hemostatic system and hemodynamic parameters in patients with a history of a "diurnal" and "nocturnal" stroke were identified. A conclusion is drawn that the circadian distribution of acute disturbances of the cerebral blood circulation is determined by individual characteristics of some circadian rhythms of the patients' bodies.
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