[Features of the initial manifestations of Alzheimer's disease]

On the basis of a retrospective analysis of characteristics of the initial stage of Alzheimer's disease the authors showed its variability with regard to both clinical manifestations and duration. It was found that the psychopathological structure and increase in disturbances at the initial stage of Alzheimer's disease correlated with the age at the onset of the disease. In some cases an increase in its clinical manifestations could be correlated with definite pretreatment personality peculiarities of the patients. In some patients the cortical focal disorders and intellectual dysfunctions with which dementia first manifested itself became most pronounced in the advanced stage of the pathological process.