Related Experiment Video
Updated: Jul 15, 2025
Design and Development of Aptamer–Gold Nanoparticle Based Colorimetric Assays for In-the-field Applications
Published on: June 23, 2016
Development of a Colorimetric Paper Sensor for Hg2+ Detection in Water Using Cyanuric Acid-Conjugated Gold
Febrina Amelia Saputri1, Eka Ulya Zubaidah1, Amaranggani Wikan Puspita Kenanga1
1Faculty of Pharmacy, Universitas Indonesia, Depok 16424, Indonesia.
Abstract:
Hg2+ is one of the most dangerous pollutants that can cause damage to organs and the immune system. The common detection methods of Hg2+ require sophisticated instrumentation and a long time for analysis. The purpose of this study was to develop a sensor for the detection of Hg2+ using filter paper immobilized by gold nanoparticles (AuNPs) conjugated with cyanuric acid (CA). The clear color change from pink to bluish purple is the response of the CA-AuNPs filter paper sensor to exposure to Hg2+. Detection can be observed visually with the naked eye and/or with imageJ software; the detection limit is 0.05 µM. The colorimetric response of the sensor was also selective towards Hg2+ after testing with different metal ions. In addition, the response from the sensor was also consistent for lake water samples spiked with Hg2+. The results of this research provide a promising basic technology for the development of sensors that are affordable, fast, portable, and easy to use for the detection and monitoring of Hg2+ levels in water.
