Related Experiment Video
Updated: Jul 15, 2025

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
The Need for Culturally Appropriate Food Allergy Management Strategies: The Indian Milk Ladder
Somashekara Hosaagrahara Ramakrishna1, Neil Shah2,3, Bhaswati C Acharyya4,5
1Department of Paediatric Hepatology & Gastroenterology, Gleneagles Global Health City, Chennai 600100, India.
The Indian Milk Ladder is a new tool to help manage cow's milk allergy (CMA) in children. It uses Indian foods to guide the introduction of milk, promoting oral tolerance and easing dietary restrictions.
Area of Science:
- Pediatric Allergy and Immunology
- Clinical Nutrition
- Food Science
Background:
- Cow's milk allergy (CMA) is a prevalent and complex condition in infants globally.
- Baked milk products are often tolerated by children with CMA, allowing for relaxed dietary restrictions.
- Early introduction of tolerated allergenic foods can promote oral tolerance and potentially outgrow the allergy.
Purpose of the Study:
- To develop a comprehensive milk ladder tailored to Indian dietary habits.
- To validate the milk protein content of Indian foods for allergy management.
- To facilitate the safe reintroduction of milk into the diets of children with CMA.
Main Methods:
- Convened an expert group to create a milk ladder based on Indian foods.
- Calculated and validated the milk protein content of selected Indian foods.
- Re-evaluated the ladder based on cooked milk protein content and cooking parameters.
Main Results:
- Developed the first milk ladder featuring Indian foods with validated milk protein content.
- The ladder includes specific information on the timing and temperature of cooking for each food.
- Expert consensus and laboratory validation underpin the ladder's structure.
Conclusions:
- The Indian Milk Ladder is the first to incorporate unique Indian food habits and expert consensus.
- It provides validated milk protein quantification for each step, aiding in CMA management.
- This tool is expected to be valuable for pediatricians, parents, and caregivers in India and globally.
Related Concept Videos
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Allergic Drug Reactions
Allergic Reactions
Hypersensitivities
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Asthma-IV: Nursing Management
First, in...

