Related Experiment Video
Updated: Jul 15, 2025
08:48
Identification of Neutrophil Extracellular Traps in Paraffin-Embedded Feline Arterial Thrombi using Immunofluorescence Microscopy
Published on: March 29, 2020
8.6K
Feline Infectious Peritonitis: European Advisory Board on Cat Diseases Guidelines
Séverine Tasker1,2, Diane D Addie3, Herman Egberink4
1Bristol Veterinary School, University of Bristol, Bristol BS40 5DU, UK.
Viruses
|September 28, 2023
Summary
Feline infectious peritonitis (FIP) is a serious disease caused by feline coronavirus (FCoV). New antiviral treatments, like nucleoside analogues, now offer recovery for many cats with FIP.
Area of Science:
- Veterinary Medicine
- Virology
- Immunology
Background:
- Feline coronavirus (FCoV) is a common RNA virus in cats, typically spread via fecal-oral transmission.
- While most FCoV infections are asymptomatic or cause mild enteritis, a subset of infected cats develop fatal feline infectious peritonitis (FIP).
Purpose of the Study:
- To provide comprehensive guidelines on the diagnosis and management of feline infectious peritonitis (FIP).
- To review the pathology, clinical signs, diagnostic approaches, and treatment options for FIP.
Main Methods:
- Review of existing literature and clinical guidelines by the European Advisory Board on Cat Diseases (ABCD).
- Discussion of diagnostic techniques including effusion analysis (cytology, biochemistry, FCoV RNA/antigen detection), fine-needle aspirates, and histopathology with FCoV antigen detection.
- Evaluation of current and emerging antiviral treatments.
Main Results:
- FIP pathology involves perivascular phlebitis affecting various organs, predominantly in cats under two years old.
- Common clinical signs include fever, anorexia, weight loss, effusions, and potentially ocular or neurological symptoms.
- Diagnostic challenges are addressed with tools aiding veterinarians, with definitive diagnosis often requiring histopathology.
Conclusions:
- Antiviral therapies, particularly nucleoside analogues like GS-441524, have significantly improved recovery rates for FIP.
- Despite treatment advancements, accessibility of these antivirals may vary by country.
Related Concept Videos
01:30Acute Pancreatitis II: Clinical Manifestations and Management
142
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
142
01:27Acute Pancreatitis I: Introduction
393
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
393
01:29Chronic Pancreatitis II: Collaborative Care
108
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
108