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An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
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Infected aortic endograft with an unusual microbe, Burkholderia cepacia

Evan E Foulke1, Benjamin C Powell2, Brett Salomon1

  • 1Department of Surgery, University of Tennessee Medical Center, University of Tennessee Graduate Medical Education, Knoxville, TN.

Journal of Vascular Surgery Cases and Innovative Techniques
|September 28, 2023
PubMed

Insights

Endovascular graft infections after aortic repair can occur. This study details two cases of aortic graft infection caused by Burkholderia cepacia, successfully treated with explantation and revascularization.

Area of Science:

  • Vascular Surgery
  • Infectious Diseases
  • Microbiology

Background:

  • Endovascular aortic repair (EVAR) is increasingly used for aortic aneurysms.
  • Graft infections following EVAR are a recognized complication.
  • Individualized treatment is crucial, considering the causative organism.

Observation:

  • Two patients developed endovascular graft infections after EVAR using the same endograft.
  • The infections were caused by Burkholderia cepacia, a gram-negative organism.
  • Genetic testing revealed distinct, unrelated strains of Burkholderia cepacia in each patient.

Findings:

  • Both patients underwent successful endograft explantation.
  • Revascularization procedures were performed without immediate complications.
  • The study highlights successful management of rare EVAR graft infections.

Implications:

  • This case series contributes to understanding Burkholderia cepacia as a pathogen in EVAR infections.
  • Successful explantation and revascularization are feasible treatment options.
  • Further research may elucidate risk factors and optimal management strategies for EVAR graft infections.
Keywords:
Burkholderia cepaciaEndograft infection

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