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Updated: Jul 15, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Translating evidence-based knowledge objects into practice.
1Department of Social Sciences and Business, Roskilde University, Roskilde, Denmark.
Organizational translation theories offer a novel process perspective for implementation science, explaining how healthcare knowledge objects are adapted and spread by individuals over time and space. This approach enhances understanding of knowledge implementation in practice.
Area of Science:
- Health Services Research
- Organizational Studies
- Knowledge Translation
Background:
- Implementation science often focuses on general factors influencing knowledge adoption.
- Organizational translation theories provide a process-oriented view of how knowledge is spread and transformed.
Purpose of the Study:
- To demonstrate how organizational translation theories can enrich implementation science.
- To introduce a process perspective on the implementation of knowledge objects in healthcare.
Main Methods:
- Utilizing Bruno Latour's concept of translation to understand knowledge dissemination.
- Analyzing the role of individual actors (translators) in modifying or appropriating knowledge.
- Examining the sequence of events, activities, and choices in knowledge translation processes.
Main Results:
- Proposes that the spread and modification of knowledge objects are driven by individual actions.
- Highlights the dynamic nature of knowledge implementation through human interaction.
- Suggests translation theories offer a detailed, situated understanding of implementation outcomes.
Conclusions:
- Organizational translation theories offer a valuable supplement to implementation science by providing a dynamic, actor-centered process view.
- Further research can explore propositions on knowledge object translation in healthcare organizations.
- Integrating these perspectives can deepen the understanding of how evidence-based practices are adopted and adapted in real-world settings.
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