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Mie Dyberg Skandov1, Ellen Astrid Holm1

  • 1Medicinsk Afdeling, Sjællands Universitetshospital, Køge.

Ugeskrift for Laeger
|September 28, 2023
PubMed
Summary

This review evaluates tools for deprescribing in older frail patients, identifying eight helpful resources. Further research is needed to strengthen evidence on deprescribing tools and patient outcomes.

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Area of Science:

  • Geriatric Medicine
  • Pharmacology
  • Clinical Pharmacy

Background:

  • Older frail patients with multiple diagnoses and extensive medication regimens face significant risks.
  • These risks include adverse drug events, harmful drug interactions, and polypharmacy (unnecessary medication).
  • Effective deprescribing strategies are crucial for improving patient safety and quality of life in this population.

Approach:

  • This review systematically evaluated existing tools designed to aid in the deprescribing process for older, frail individuals.
  • Eight distinct deprescribing tools were identified and categorized into three distinct levels of application.
  • The review assessed the contribution of these tools to understanding and implementing deprescribing interventions.

Key Points:

  • Eight deprescribing tools were identified and organized into three hierarchical levels.
  • All reviewed tools offer valuable insights and practical support for deprescribing.
  • The current evidence base supporting the efficacy of these deprescribing tools requires further expansion.

Conclusions:

  • Existing deprescribing tools offer a foundation for managing complex medication regimens in frail older adults.
  • Further research is essential to build robust evidence for the effectiveness of these tools.
  • Investigating patient-specific barriers and measurable clinical outcomes is critical for optimizing deprescribing practices.

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