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Related Experiment Video

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Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

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The EORTC QLU-C10D: the Hong Kong valuation study.

Richard Huan Xu^1,2, Eliza Lai-Yi Wong³, Nan Luo⁴

¹Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, China. richard.xu@polyu.edu.hk.

The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care

|September 28, 2023

Summary

This study developed Hong Kong utility weights for the EORTC QLU-C10D cancer measure. These values enable cost-utility analyses of cancer interventions in Hong Kong.

Keywords:

Decision making Discrete choice experiment EORTC QLQ-C30 Hong Kong QLU-C10D Quality of life Utility weights

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Published on: June 14, 2021

Area of Science:

Health Economics
Oncology
Psychometrics

Background:

The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC) QLU-C10D is a preference-based measure.
Country-specific value sets are essential for cost-utility analyses of cancer interventions.

Purpose of the Study:

To generate a Hong Kong (HK) specific value set for the EORTC QLU-C10D.
To support cost-utility analyses of cancer-related health programs and technologies in HK.

Main Methods:

An online discrete choice experiment survey was administered to a quota-sampled HK general population panel.
Conditional and mixed logistic regression analyses were used to analyze data from 1041 respondents.
Weighting analysis was applied to address non-representative age distribution.

Main Results:

The mean EORTC QLU-C10D utility score was 0.804 (median 0.838).
Largest utility decrements were observed for physical functioning (-0.308), role functioning (-0.165), and pain (-0.161).
The worst health state utility value was -0.223, indicating a value lower than death.

Conclusions:

Established HK utility weights for the EORTC QLU-C10D.
These weights will facilitate robust cost-utility analyses for cancer interventions in Hong Kong.