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Related Experiment Videos

Autopsy. High yield in neonatal population.

H Craft, J E Brazy

    American Journal of Diseases of Children (1960)
    |December 1, 1986
    PubMed
    Summary

    Neonatal autopsies frequently yield significant findings, including congenital anomalies and infections. This valuable data aids in diagnosis, genetic counseling, and patient care, supporting their continued use.

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    Area of Science:

    • Medical research
    • Pediatric pathology

    Background:

    • The clinical value of autopsies is debated, with limited data on pediatric cases.
    • Neonatal autopsies are crucial for understanding infant mortality and improving care.

    Purpose of the Study:

    • To evaluate the frequency and utility of neonatal autopsies in a level III neonatal intensive care unit.
    • To compare clinical diagnoses with autopsy findings.

    Main Methods:

    • Retrospective review of 113 neonatal deaths over three years.
    • Comparison of clinically active problems with final autopsy diagnoses.
    • Tabulation of significant autopsy findings.

    Main Results:

    • Autopsies were performed in 63% of cases, revealing significant findings in 39%.
    • Key findings included congenital anomalies (16%), infections (9%), and iatrogenic complications (5%).
    • Autopsies confirmed diagnoses in 16% and influenced genetic counseling or patient care monitoring in 18.3%.

    Conclusions:

    • Neonatal autopsies provide valuable diagnostic information and impact patient management.
    • Gross examination is the most informative component of the neonatal autopsy.
    • A high rate of neonatal autopsy is supported by its significant diagnostic yield.

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