Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hand hygiene01:23

Hand hygiene

3.3K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
3.3K
Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

49
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
49
Methods of Sterilization II: Chemical Methods01:30

Methods of Sterilization II: Chemical Methods

6.5K
In healthcare, the chemical method of sterilization uses chemical sterilants to treat surgical instruments and medical supplies to help prevent the transmission of infectious pathogens to patients. Due to heat sensitivity, most medical supplies and equipment should not be exposed to high temperatures. These parts include rubber, plastic, glass, and other similar elements.
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
6.5K
Oxidation of Phenols to Quinones01:17

Oxidation of Phenols to Quinones

3.1K
In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
3.1K
Anticholinesterase Agents: Poisoning and Treatment01:26

Anticholinesterase Agents: Poisoning and Treatment

908
Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.     
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
908
Cleaning, Sterilization, and Disinfection01:30

Cleaning, Sterilization, and Disinfection

7.0K
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
7.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Safety Assessment of <i>Melaleuca alternifolia</i> (Tea Tree)-Derived Ingredients as Used in Cosmetics.

International journal of toxicology·2026
Same authorSame journal

Safety Assessment of Radish Root - Derived Ingredients as Used in Cosmetics.

International journal of toxicology·2026
Same authorSame journal

Amended Safety Assessment of Naturally-Sourced Clays as Used in Cosmetics.

International journal of toxicology·2026
Same author

Safety Assessment of Diatomaceous Earth as Used in Cosmetics.

International journal of toxicology·2026
Same author

Safety Assessment of Basic Yellow 87 as Used in Cosmetics.

International journal of toxicology·2026
Same author

Safety Assessment of Glycolactones as Used in Cosmetics.

International journal of toxicology·2026
Same journal

Aldose Reductase Inhibitor, Epalrestat, Suppresses Colorectal Cancer Cell Proliferation Through Complement-Dependent Cytotoxicity.

International journal of toxicology·2026
Same journal

Nonclinical Safety Profiles of mRNA Therapeutics Comprising Unmodified or N1-Methyl-Pseudouridine-Modified Nucleosides Are Similar Following Repeated Administration.

International journal of toxicology·2026
Same journal

Evaluation of the <i>in vitro</i> Toxicity of Novel Oxime Acetylcholinesterase Reactivators.

International journal of toxicology·2026
See all related articles

Related Experiment Video

Updated: Jul 15, 2025

The Portable Chemical Sterilizer PCS, D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military
14:17

The Portable Chemical Sterilizer PCS, D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military

Published on: June 29, 2014

14.6K

Chloroxylenol.

Priya Cherian1, Wilma F Bergfeld2, Donald V Belsito2

  • 1Cosmetic Ingredient Review Senior Scientific Analyst/Writer, Washington, DC, USA.

International Journal of Toxicology
|September 28, 2023
PubMed
Summary
This summary is machine-generated.

The Expert Panel for Cosmetic Ingredient Safety reaffirmed that Chloroxylenol is safe for cosmetic use. Updated reviews confirm its safety in current product types, frequencies, and concentrations.

Keywords:
ChloroxylenolCosmeticsSafety

More Related Videos

A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens
09:02

A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens

Published on: June 7, 2017

19.2K
Controlled-release of Chlorine Dioxide in a Perforated Packaging System to Extend the Storage Life and Improve the Safety of Grape Tomatoes
07:07

Controlled-release of Chlorine Dioxide in a Perforated Packaging System to Extend the Storage Life and Improve the Safety of Grape Tomatoes

Published on: April 7, 2017

11.1K

Related Experiment Videos

Last Updated: Jul 15, 2025

The Portable Chemical Sterilizer PCS, D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military
14:17

The Portable Chemical Sterilizer PCS, D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military

Published on: June 29, 2014

14.6K
A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens
09:02

A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens

Published on: June 7, 2017

19.2K
Controlled-release of Chlorine Dioxide in a Perforated Packaging System to Extend the Storage Life and Improve the Safety of Grape Tomatoes
07:07

Controlled-release of Chlorine Dioxide in a Perforated Packaging System to Extend the Storage Life and Improve the Safety of Grape Tomatoes

Published on: April 7, 2017

11.1K

Area of Science:

  • Cosmetic Science
  • Dermatology
  • Toxicology

Background:

  • The safety of cosmetic ingredients is periodically reassessed.
  • Chloroxylenol was previously evaluated in 1985.

Purpose of the Study:

  • To review updated safety information on Chloroxylenol.
  • To assess current product use, frequency, and concentrations of Chloroxylenol.

Main Methods:

  • Review of updated scientific literature.
  • Analysis of current cosmetic product formulations and usage patterns.

Main Results:

  • Updated information on Chloroxylenol has become available since 1985.
  • Current product types, frequency, and concentrations of use were evaluated.

Conclusions:

  • Chloroxylenol is safe as a cosmetic ingredient.
  • The Expert Panel reaffirmed its original safety conclusion for Chloroxylenol.