Carbon dioxide reduction to high-value chemicals in microbial electrosynthesis system: Biological conversion and...

Large emissions of atmospheric carbon dioxide (CO₂) are causing climatic and environmental problems. It is crucial to capture and utilize the excess CO₂ through diverse methods, among which the microbial electrosynthesis (MES) system has become an attractive and promising technology to mitigate greenhouse effects while reducing CO₂ to high-value chemicals. However, the biological conversion and metabolic pathways through microbial catalysis have not been clearly elucidated. This review first introduces the main acetogenic bacteria for CO₂ reduction and extracellular electron transfer mechanisms in MES. It then intensively analyzes the CO₂ bioconversion pathways and carbon chain elongation processes in MES, together with energy supply and utilization. The factors affecting MES performance, including physical, chemical, and biological aspects, are summarized, and the strategies to promote and regulate bioconversion in MES are explored. Finally, challenges and perspectives concerning microbial electrochemical carbon sequestration are proposed, and suggestions for future research are also provided. This review provides theoretical foundation and technical support for further development and industrial application of MES for CO₂ reduction.