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Updated: Jul 15, 2025

Author Spotlight: Direct Infusion Device for Molecule Delivery in Plants
Published on: June 2, 2023
Scripting a new dialogue between diazotrophs and crops
Sanhita Chakraborty1, Maya Venkataraman2, Valentina Infante1
1Department of Bacteriology, University of Wisconsin - Madison, Madison, WI, USA.
Abstract:
Diazotrophs are bacteria and archaea that can reduce atmospheric dinitrogen (N2) into ammonium. Plant-diazotroph interactions have been explored for over a century as a nitrogen (N) source for crops to improve agricultural productivity and sustainability. This scientific quest has generated much information about the molecular mechanisms underlying the function, assembly, and regulation of nitrogenase, ammonium assimilation, and plant-diazotroph interactions. This review presents various approaches to manipulating N fixation activity, ammonium release by diazotrophs, and plant-diazotroph interactions. We discuss the research avenues explored in this area, propose potential future routes, emphasizing engineering at the metabolic level via biorthogonal signaling, and conclude by highlighting the importance of biocontrol measures and public acceptance.
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