A relational framework for microbiome research with Indigenous communities

Area of Science:

• Human microbiome research
• Bioethics
• Indigenous studies

Background:

• Ethical frameworks in human microbiome research lag behind scientific advancements.
• Historical research practices have led to intellectual and material extraction from Indigenous communities.
• There's a need to address power imbalances and incorporate Indigenous perspectives in microbiome research.

Purpose of the Study:

• To propose a new ethical framework for human microbiome research.
• To center relationality and accountability in research involving Indigenous peoples and microbes.
• To advance Indigenous research sovereignty and ensure equitable benefit sharing.

Main Methods:

• Development of a framework based on relationality and accountability.
• Emphasis on co-production of knowledge and inclusion of Indigenous worldviews.
• Addressing historical power imbalances in research partnerships.

Main Results:

• The proposed framework prioritizes Indigenous research sovereignty.
• It aims to flatten power imbalances favoring researchers.
• It creates space for Indigenous perspectives in microbiome research.

Conclusions:

• Ethical microbiome research must actively include Indigenous communities.
• Implementing this framework can lead to health benefits for all populations.
• It fosters mutually beneficial partnerships between researchers and the public.