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An algorithmic approach to sinonasal evaluation preceding bone marrow transplantation
Matin Ghazizadeh1, Golfam Mehrparvar2, Maryam Ghazizadeh3
1Department of Otorhinolaryngology Head and Neck Surgery, Taleghani Hospital, Shahid Beheshti Univsity of Medical Sciences, Tehran, Iran.
Otolaryngologia Polska = the Polish Otolaryngology
|September 29, 2023
Summary
This study proposes a new algorithm for pre-transplant sinonasal evaluation, aiming to reduce post-transplant complications. The approach emphasizes history, physical exam, and nasal endoscopy, suggesting CT scans are not always necessary.
Area of Science:
- Otolaryngology
- Transplant Surgery
- Infectious Disease
Background:
- Sinonasal diseases pose risks for transplant recipients.
- Pre-transplant evaluation protocols vary.
- Standardized approaches are needed to mitigate post-transplant morbidity.
Purpose of the Study:
- To review existing literature on pre-transplant sinonasal evaluation.
- To develop a structured algorithmic approach for this assessment.
- To reduce post-transplantation morbidity and mortality.
Main Methods:
- Systematic literature search of PubMed, Cochrane, and Google Scholar.
- Inclusion of English-language studies on rhinosinusitis and transplantation.
- Development of a clinical algorithm based on reviewed evidence.
Main Results:
- 35 relevant studies identified from 182 initial articles.
- An algorithmic approach for sinonasal evaluation was formulated.
- The algorithm prioritizes clinical assessment over routine imaging.
Conclusions:
- A comprehensive, cost-effective algorithm for pre-transplant sinonasal evaluation is proposed.
- The algorithm aids in identifying and managing sinonasal issues before immunosuppression.
- Implementation may decrease post-transplant complications and improve patient outcomes.
