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Related Concept Videos

Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
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The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
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The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
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Related Experiment Video

Updated: Jul 15, 2025

Author Spotlight: Dendritic Cells Maturation Using Sialidases-Based Enzymatic Treatment of the Cell Surface
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Lysosomal control of dendritic cell function.

Jia Yang1, Shan-Jie Rong2, Hai-Feng Zhou1

  • 1Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue No.1277, 430000, Wuhan, China.

Journal of Leukocyte Biology
|September 29, 2023
PubMed
Summary
This summary is machine-generated.

Lysosomes are dynamic organelles crucial for dendritic cell (DC) function, regulating motility, immune signaling, and antigen presentation. Targeting lysosomes offers promising DC-based immunotherapies for various diseases.

Area of Science:

  • Immunology
  • Cell Biology
Keywords:
DC-based immunotherapydendritic cell (DC)immune responselysosome

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Background:

  • Lysosomes are traditionally viewed as digestive organelles.
  • Recent research highlights their dynamic roles in cell function.

Conclusions:

  • Lysosomes are versatile regulators of DC biology, extending beyond digestion.
  • Lysosome-targeting strategies represent a significant approach for DC-based immunotherapies against tumors, infections, and autoinflammatory disorders.