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Updated: Jul 15, 2025

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
Delivering trials in the NHS: more than worth it
Richard Haynes1, Marion Mafham2, Cheng Hock Toh3
1Nuffield Department of Population Health, University of Oxford, Oxford, UK, and chief scientist, Protas, Salford, UK.
Randomised trials are crucial for assessing health technology. Integrating trials into all NHS institutions and doctors' work, using routine data, can boost efficiency, job satisfaction, and public health.
Area of Science:
- Health technology assessment
- Clinical trial methodology
- Healthcare system improvement
Background:
- Randomised trials are the gold standard for evaluating health technology efficacy and safety.
- A recent report identified significant challenges in delivering clinical trials within the UK.
- Opportunities exist to enhance trial delivery and healthcare outcomes.
Purpose of the Study:
- To explore solutions for improving clinical trial delivery in the UK.
- To investigate the integration of trials into routine NHS practice.
- To leverage routinely collected NHS data for research purposes.
Main Methods:
- Analysis of challenges and proposed solutions from a recent UK report on clinical trials.
- Conceptual framework for integrating trials into NHS institutions and medical practice.
- Exploration of data leveraging from routine NHS collections.
Main Results:
- Making trials a core function of NHS institutions and a valued part of doctors' work is proposed.
- Leveraging routinely collected NHS data offers a pathway to streamline trial processes.
- Simultaneous improvements in NHS efficiency, doctor job satisfaction, and population health are anticipated.
Conclusions:
- Integrating clinical trials more deeply into the NHS infrastructure is essential.
- Utilizing existing NHS data infrastructure can significantly enhance research efficiency.
- A strategic shift can lead to a more effective healthcare system and improved patient outcomes.
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