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Updated: Jul 15, 2025

Cone Beam Intraoperative Computed Tomography-based Image Guidance for Minimally Invasive Transforaminal Interbody Fusion
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Management Considerations for Total Intervertebral Disc Replacement.

Marco Foreman1, Aashay Patel1, Andrew Nguyen1

  • 1Department of Neurosurgery, University of Florida, Gainesville, Florida, USA.

World Neurosurgery
|September 30, 2023
PubMed
Summary
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Total disc replacement (TDR) offers a modern solution for chronic neck and back pain, addressing limitations of traditional spinal surgeries like fusion and discectomy. This review explores TDR as an innovative treatment option for spinal conditions.

Area of Science:

  • Spine surgery
  • Orthopedics
  • Neurosurgery

Background:

  • Lumbar and cervical spine pain represent a significant global health burden, causing chronic pain, disability, and high healthcare utilization.
  • Traditional treatments like spinal fusion and discectomy, while effective short-term, have limitations including reduced spinal mobility and potential complications.
  • Increasing life expectancy and chronic disease prevalence exacerbate the need for improved spinal pain management strategies.

Purpose of the Study:

  • To review the management strategy of intervertebral disc arthroplasty (total disc replacement, TDR).
  • To explore updated considerations for the clinical application of TDR.
  • To guide clinical decision-making in the treatment of lumbar and cervical spine pain.

Main Methods:

Keywords:
Degenerative disc diseaseIntervertebral disc arthroplastyTotal disc replacement

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  • Literature review of studies on intervertebral disc arthroplasty (TDR).
  • Analysis of TDR efficacy, complications, and comparison with traditional spinal surgeries.
  • Synthesis of current evidence and expert considerations for TDR implementation.

    • Main Results:

    • Traditional spinal surgeries (fusion, discectomy) can lead to impaired range of motion and postoperative complications.
    • Total disc replacement (TDR) is presented as a modern alternative to traditional spinal fusion and discectomy.
    • Updated considerations for TDR use in clinical practice are discussed.

    Conclusions:

    • Total disc replacement (TDR) presents a promising innovation for managing debilitating lumbar and cervical spine pain.
    • TDR may offer an alternative to traditional fusion and discectomy, potentially mitigating some long-term adverse effects.
    • Further exploration of TDR's role in clinical practice is warranted to optimize patient outcomes for spinal conditions.