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Related Concept Videos

Bacterial Phylum Tenericutes01:24

Bacterial Phylum Tenericutes

36
The phylum Tenericutes, which includes the single class Mollicutes, comprises bacteria that lack cell walls. The term "Mollicutes" derives from the Latin word mollis, meaning "soft." These organisms are among the smallest known and are commonly referred to as mycoplasmas due to the prominence of the genus Mycoplasma, which includes well-known human pathogens. Despite their inability to stain gram-positively (a result of their lack of cell walls), mycoplasmas are phylogenetically related to the...
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Microbial Classification System01:24

Microbial Classification System

38
Classification is the process of organizing organisms into hierarchically inclusive groups based on their phenotypic similarities or evolutionary relationships. A species comprises one or more strains, and closely related species are grouped into genera. Genera are further classified into families, families into orders, orders into classes, and so forth, up to the domain level, which is the broadest taxonomic rank derived from a combination of phenotypic and genotypic data.The nomenclature of...
38
Bacterial Phylum Firmicutes01:27

Bacterial Phylum Firmicutes

38
Firmicutes is a diverse phylum of Gram-positive bacteria characterized by a low GC content in their genomes. This phylum includes organisms with monoderm or diderm cell envelopes, highlighting a complex evolutionary history. Firmicutes comprises several major orders, including Lactobacillales, Clostridiales, and Bacillales, which exhibit remarkable diversity in their morphology, metabolism, and ecological roles.The order Lactobacillales includes lactic acid bacteria, which are fermentative...
38
Bacterial Phylum Actinobacteria01:30

Bacterial Phylum Actinobacteria

31
Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
31
Bacterial Phylum Verrucomicrobiota01:26

Bacterial Phylum Verrucomicrobiota

30
The phylum Verrucomicrobiota comprises at least four characterized orders, with most species classified within the order Verrucomicrobiotales. Members of this phylum are either aerobic or facultatively aerobic, with the ability to ferment sugars. A notable exception is the genus Methylacidiphilum, which consists of aerobic methanotrophs. Additionally, some Verrucomicrobiota establish symbiotic relationships with protists. These bacteria are widely distributed across various environments,...
30
Bacterial Phylum Bacteroidota01:26

Bacterial Phylum Bacteroidota

38
The phylum Bacteroidota includes over 700 species classified into four primary orders: Bacteroidales, Cytophagales, Flavobacteriales, and Sphingobacteriales. These gram-negative, non-sporulating rods exhibit saccharolytic capabilities and can be aerobic or fermentative, encompassing obligate aerobes, facultative aerobes, and obligate anaerobes. Many species display gliding motility, though some are nonmotile or use flagella. The genus Bacteroides is well-studied due to its significant role in...
38

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A Workflow for the Quantitative Assessment of the Endophytic and Epiphytic Bacterial Microbiomes of the Bark of Populus trichocarpa
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Acne microbiome: From phyla to phylotypes.

Brigitte Dreno1, Itaru Dekio2, Hilary Baldwin3

  • 1Dermatology Department, INSERM, CNRS, Immunology and New Concepts in ImmunoTherapy, INCIT, UMR 1302/EMR6001, Nantes Université, Nantes, France.

Journal of the European Academy of Dermatology and Venereology : JEADV
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Summary

Acne vulgaris involves more than just Cutibacterium acnes; skin microbiome imbalances and Staphylococcus epidermidis also play roles. New dermocosmetic strategies are needed to support skin health and manage acne effectively.

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Area of Science:

  • Dermatology
  • Microbiology
  • Skin Health

Background:

  • Acne vulgaris is a complex inflammatory skin condition.
  • Traditionally attributed to sebum, inflammation, keratinization, and Cutibacterium acnes (C. acnes).
  • The precise role of C. acnes in acne pathogenesis has been debated due to its common presence on skin.

Purpose of the Study:

  • To explore the evolving understanding of C. acnes and other microbes in acne development.
  • To investigate the impact of current acne treatments on the skin microbiome.
  • To identify new therapeutic avenues for acne management.

Main Methods:

  • Review of recent research on acne pathogenesis.
  • Analysis of the role of C. acnes phylotypes and skin microbiome.
  • Consideration of the impact of antibiotics on skin microbiota.

Main Results:

  • Evidence suggests acne is triggered by an imbalance in C. acnes phylotypes and alterations in the skin microbiome.
  • Staphylococcus epidermidis is identified as a contributing factor in acne development.
  • Antibiotics, a common acne treatment, can induce cutaneous dysbiosis.

Conclusions:

  • Acne pathogenesis is influenced by a complex interplay of skin microbes, including C. acnes and S. epidermidis.
  • The overuse of antibiotics in acne treatment necessitates alternative strategies.
  • Dermocosmetic products supporting skin barrier function and microbiome health offer a promising direction for acne management.