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Outpatient management of established bronchopulmonary dysplasia: An update
Anita Bhandari1, Stamatia Alexiou1
1Division of Pulmonary and Sleep Medicine, Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, 34th and Civic Center Blvd. Philadelphia, PA 19104, United States.
Insights
Bronchopulmonary dysplasia (BPD) management in infants is complex, involving multiple therapies and multidisciplinary care. More research is needed to confirm the effectiveness of current treatments for BPD survivors.
Area of Science:
- Neonatology
- Pediatric Pulmonology
Background:
- Rising incidence and survival rates of infants with bronchopulmonary dysplasia (BPD).
- Complex medical management of BPD necessitates diverse therapies and specialized care.
Approach:
- Review of widely used outpatient therapies for established BPD.
- Focus on post-neonatal intensive care management strategies.
Key Points:
- Commonly used therapies include steroids, bronchodilators, diuretics, oxygen, and positive pressure support.
- Multidisciplinary care is crucial for optimizing growth and neurodevelopmental outcomes.
- Evidence supporting many current BPD therapies is limited.
Conclusions:
- Established BPD requires comprehensive management involving various medical interventions.
- High-quality research, including randomized controlled trials, is essential to validate treatment efficacy.
- Further studies are needed to define optimal outcomes for BPD management.
Abstract:
As the incidence of infants with bronchopulmonary dyspasia (BPD) has continued to rise, so has their rate of survival. Their medical management is often complex and requires the use of numerous therapies such as steroids, bronchodilators, diuretics and modalities to deliver supplemental oxygen and positive pressure. It also requires multi-disciplinary care to ensure adequate growth and to optimize neurodevelopmental outcomes. This review aims to discuss the most widely used therapies in the treatment of patients with established BPD. The focus will be on ongoing outpatient (post-neonatal intensive care) management of children with BPD. Since many of the mentioned therapies lack solid evidence to support their use, more high quality research, such as randomized controlled trials, is needed to assess their effectiveness using defined outcomes.
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