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Characterization of refeeding protocols for under 18 years old hospitalized patients with anorexia nervosa: A
Helen Cristina Bittencourt Lopes1, Bruna Caruso Mazzolani2, Priscila Koritar3
1Nutrition and Dietetics Service and Interdisciplinary Project for Care, Teaching, and Research on Eating Disorders in Childhood and Adolescence (PROTAD), Institute of Psychiatry, University of São Paulo, São Paulo, Brazil.
Insights
This review found significant variability in refeeding protocols for hospitalized anorexia nervosa (AN) patients under 18. More research is needed to establish effective guidelines for treating adolescent AN.
Area of Science:
- Pediatric Endocrinology
- Eating Disorders Research
- Clinical Nutrition
Background:
- Anorexia nervosa (AN) is a serious eating disorder affecting adolescents.
- Refeeding is a critical but complex component of AN treatment.
- Standardized protocols for pediatric AN refeeding are lacking.
Purpose of the Study:
- To characterize and compare existing refeeding protocols for hospitalized patients under 18 with AN.
- To identify commonalities and variations in current refeeding practices.
- To highlight the need for evidence-based guidelines.
Main Methods:
- Systematic review of multiple databases (PubMed, Cochrane, etc.).
- Inclusion criteria based on PICOS framework.
- Analysis of 20 eligible studies out of 412 initially found.
Main Results:
- Significant heterogeneity in sample sizes, refeeding protocols, and treatment durations observed.
- Most studies were observational or retrospective, with 80% published recently.
- Methodological limitations were present across included studies.
Conclusions:
- Current refeeding protocols for adolescent AN exhibit considerable variability.
- Methodological limitations and study design heterogeneity hinder definitive conclusions.
- Prospective trials are essential to compare standard protocols and establish optimal care for this population.
Purpose:
To characterize and compare, through descriptive analysis, existing refeeding protocols for under 18 years old hospitalized patients with anorexia nervosa (AN).
Methods:
This is a systematic review of PubMed, Cochrane, SciELO, Lilacs and BVS databases, without search period restriction. Studies were selected in accordance with pre-defined eligibility criteria and according to the Population, Intervention, Comparator, Outcome and Study Design (PICOS).
Results:
Twenty articles out of 412 found complied with PICOS eligibility criteria and were included in the final review. Most of the studies were observational or retrospective and 80% were published in the last decade. Large variability in relation to sample size, refeeding protocols and length of stay were observed between studies.
Conclusion:
All included studies had several methodological limitations and heterogeneous designs, making it difficult to establish conclusive guidelines regarding the most adequate and effective refeeding protocol for under 18 years old hospitalized patients with AN. Prospective trials are necessary to straight compare standard refeeding protocols for this population.
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