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Next-generation sequencing (NGS) is vital for public health. Africa CDC trained over 400 professionals in genomics and bioinformatics to boost pathogen surveillance across the continent.

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Area of Science:

  • Genomic Epidemiology
  • Public Health
  • Bioinformatics

Background:

  • Genomic data analysis via next-generation sequencing (NGS) is crucial for public health surveillance, research, and precision medicine.
  • Africa faces significant challenges in genomics and bioinformatics expertise, research opportunities, and infrastructure, hindering NGS adoption.
  • Factors contributing to the expertise gap include underfunding, inadequate training facilities, and brain drain.

Purpose of the Study:

  • To address the shortage of genomics and bioinformatics expertise in Africa.
  • To expand the continent's workforce in pathogen surveillance using genomic technologies.
  • To enhance genomic-informed public health practices in response to global health challenges like the COVID-19 pandemic.

Main Methods:

  • The Africa Centres for Disease Control and Prevention (Africa CDC), through the Africa Pathogen Genomics Initiative, implemented a training program.
  • Collaboration with partners and centers of excellence was key to program delivery.
  • Training focused on genomics, bioinformatics, and genomic epidemiology for personnel from public health institutions.

Main Results:

  • By the end of 2022, 413 personnel were trained across 53 African Union Member States (96% coverage).
  • The initiative successfully increased literacy in genomics, bioinformatics, and genomic epidemiology.
  • Trained personnel are now better equipped for genomic-informed pathogen surveillance.

Conclusions:

  • The Africa Pathogen Genomics Initiative has made significant strides in building Africa's genomics workforce.
  • While training has improved capacity, a need for strategic and sustainable public health workforce development in genomics persists.
  • Continued investment and strategic planning are essential for long-term genomic capacity building in Africa.