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Related Experiment Videos

Traumatic granuloma/eosinophilic ulcer.

R Zain, J Abdul Hamid, M N Awang

    Annals of the Academy of Medicine, Singapore
    |July 1, 1986
    PubMed
    Summary

    This study presents two cases of a rare oral ulcerative lesion that mimics malignancy but is benign. Various treatments, including surgical excision and cryosurgery, effectively resolved the lesion.

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    Area of Science:

    • Oral Pathology
    • Dermatology
    • Oncology

    Background:

    • Oral ulcerative lesions can present diagnostic challenges, sometimes mimicking malignant conditions.
    • Understanding benign reactive lesions is crucial for accurate diagnosis and appropriate management.

    Observation:

    • Two cases of uncommon oral ulcerative lesions with long duration are reported.
    • These lesions clinically resemble malignant ulcers but are histologically benign and reactive.
    • Histological examination reveals deep lesions with 'pseudoinvasion' into skeletal muscle.

    Findings:

    • A predominance of eosinophils alongside chronic inflammatory cells like plasma cells and histiocytes is noted.
    • Literature review indicates diverse treatment modalities have been employed.
    • All reviewed treatments, including surgical excision, biopsy, radiation, and cryosurgery, resulted in lesion resolution.

    Implications:

    • Accurate histological assessment is vital to differentiate these benign lesions from oral cancer.
    • The benign nature and consistent resolution with various treatments offer a favorable prognosis.
    • Awareness of this entity aids clinicians in avoiding unnecessary aggressive interventions for potentially malignant-appearing oral ulcers.

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