Related Experiment Video

Updated: Jul 15, 2025

Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis
07:45

Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis

Published on: February 9, 2021

3.6K

Uptake of the Gout and Crystal Arthritis Network Consensus Statements for Gout Nomenclature

Ellen Prendergast1, Nicola Dalbeth2, David Bursill3

  • 1Te Whatu Ora Waitaha, Christchurch, New Zealand.

Arthritis Care & Research
|October 2, 2023
PubMed

Insights

Adherence to Gout and Crystal Arthritis Network (G-CAN) nomenclature for gout has improved since 2019. However, the use of standardized gout terminology in scientific literature still requires further enhancement for clarity.

Area of Science:

  • Rheumatology
  • Crystal Arthropathies
  • Medical Nomenclature

Background:

  • The Gout and Crystal Arthritis Network (G-CAN) established consensus statements in 2019 for gout disease element and state nomenclature.
  • Consistent terminology is crucial for clear scientific communication in rheumatology.

Purpose of the Study:

  • To assess the adherence to G-CAN's consensus nomenclature statements for gout since their publication.
  • To evaluate changes in the use of specific gout-related terms in scientific abstracts before and after the G-CAN statements were released.

Main Methods:

  • A systematic search of American College of Rheumatology and EULAR conference abstracts was conducted.
  • Abstracts published before (2016-2017) and after (2020-2021) the G-CAN statements were analyzed for the use of agreed-upon and alternative nomenclature for gout.
  • Statistical comparisons were made between the two time periods to determine significant changes in term usage.

Main Results:

  • Analysis included 988 abstracts (596 from 2016-2017, 392 from 2020-2021).
  • The use of agreed labels 'urate' (57.2% to 70.7%) and 'gout flare' (34.3% to 52.3%) significantly increased post-publication (P < 0.001 and P < 0.003, respectively).
  • The use of the label 'chronic gout' significantly decreased (4.9% to 2.0%, P = 0.02).

Conclusions:

  • Adherence to G-CAN-agreed gout nomenclature has demonstrably increased in scientific abstracts.
  • Despite improvements, the nomenclature used for gout remains imprecise, indicating a need for continued efforts.
  • Further initiatives are necessary to ensure consistent and accurate application of gout nomenclature in scientific literature.
Abstract

More Related Videos

Synovial Fluid Analysis to Identify Osteoarthritis07:51

Synovial Fluid Analysis to Identify Osteoarthritis

Published on: October 20, 2022

4.5K
Knee Arthrocentesis in Adults04:41

Knee Arthrocentesis in Adults

Published on: February 25, 2022

7.6K

Related Concept Videos

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
13.6K
Drug Nomenclature01:17

Drug Nomenclature

During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United States Adopted Name (USAN)—a generic, nonproprietary designation. Upon being listed in the United States Pharmacopeia, this nonproprietary name becomes the drug's official name. Additionally, the manufacturer assigns a proprietary name or trademark, which serves as the brand name under which the drug is marketed. It is worth noting that...
1.8K
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
15
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
13
Crystal Growth: Principles of Crystallization01:25

Crystal Growth: Principles of Crystallization

Crystallization is a phase transformation process in which crystals are precipitated from a supersaturated solution or formed from other sources. During crystallization, atoms or molecules arrange themselves into a well-defined, rigid crystal lattice to minimize energy.
Initiating crystallization involves manipulating the concentration of the solute and the temperature of the solution. Since crystal growth occurs when the ratio of concentration and solubility of the solute in the solvent...
2.1K
Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
9