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Challenges in the Management of Invasive Fungal Infections in the Middle East: Expert Opinion to Optimize Management

Reem S AlMaghrabi1, Tariq Al-Musawi2,3, Osama Albaksami4

  • 1Department of Medicine, Organ Transplant Center, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU.

Cureus
|October 2, 2023
PubMed

Insights

Invasive fungal infections (IFIs) pose a growing threat in the Middle East. Addressing challenges in diagnosis and management through multidisciplinary approaches and improved diagnostics is crucial to reduce the IFI burden.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Healthcare Management

Background:

  • Invasive fungal infections (IFIs) are a significant global health concern, particularly for critically ill and immunocompromised individuals.
  • IFI incidence has risen in Middle Eastern countries over the last two decades, necessitating improved management strategies.

Purpose of the Study:

  • To review the key challenges in diagnosing and managing IFIs in the Middle East.
  • To incorporate expert opinions for optimizing IFI patient care through a multidisciplinary approach.

Main Methods:

  • Literature review focusing on IFI epidemiology, diagnosis, and treatment in the Middle East.
  • Analysis of expert opinions to identify critical decision points in patient management.

Main Results:

  • Major challenges include limited epidemiological data, slow diagnostic tests, lack of biomarker availability, and insufficient awareness and local guidelines.
  • Complex disease management and a need for multidisciplinary involvement are highlighted.

Conclusions:

  • Implementing multidisciplinary approaches, antifungal stewardship, and rapid diagnostics are essential.
  • Enhanced epidemiological research and education are vital to mitigate the IFI burden in the Middle East.
Keywords:
antifungal treatmentepidemiologyinvasive fungal infectionsmiddle eastmultidisciplinary team

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