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Related Concept Videos

Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

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Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
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Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

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Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
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Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

112
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
112
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

127
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
127
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

183
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
183
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

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Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
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Related Experiment Video

Updated: Jul 15, 2025

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection
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Esophagitis Dissecans Superficialis: A Case Report.

Eli A Zaher1, Parth Patel1, Daria Zaher2

  • 1Department of Internal Medicine, Ascension Saint Joseph Hospital, Chicago, USA.

Cureus
|October 2, 2023
PubMed
Summary

Esophagitis dissecans superficialis (EDS) is a rare esophageal condition causing mucosal sloughing. This case highlights EDS as a potential cause of unexplained weight loss, managed with proton pump inhibitors.

Keywords:
endoscopyesophagitis dissecans superficialisparakeratosisproton pump inhibitors (ppis)weight loss

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Area of Science:

  • Gastroenterology
  • Esophageal Pathology

Background:

  • Esophagitis dissecans superficialis (EDS) is a rare esophageal lesion.
  • Characterized by sloughing of the esophageal mucosa.
  • Typically asymptomatic and diagnosis relies on endoscopic appearance.

Observation:

  • An 81-year-old female presented with significant unexplained weight loss.
  • Upper endoscopy revealed severe mucosal sloughing in the lower esophagus.
  • Histopathology confirmed the diagnosis of EDS.

Findings:

  • No specific offending agents were identified in this case.
  • High-dose proton pump inhibitors (PPIs) were initiated for treatment.
  • The patient experienced symptom improvement following PPI therapy.

Implications:

  • EDS should be considered in the differential diagnosis of unexplained weight loss.
  • Management involves identifying and discontinuing potential causative agents.
  • Proton pump inhibitor therapy is a key component of EDS treatment.