The Eaton-Lambert (myasthenic) syndrome in association with systemic lupus erythematosus

We describe a case of the Eaton-Lambert (myasthenic) syndrome (ELS) in a 56-year-old woman with systemic lupus erythematosus. Treatment with successive courses of plasmapheresis produced clinical and electrophysiologic improvement in her ELS, without affecting her systemic lupus erythematosus. This case supports both the association of ELS with autoimmune disorders, and the use of plasmapheresis in the treatment of ELS.