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Oscillatory dynamics in a reaction network based on imine hydrolysis.

Emese Lantos1, Ágota Tóth1, Dezső Horváth2

  • 1Department of Physical Chemistry and Materials Science, University of Szeged, Rerrich Béla tér 1., Szeged H-6720, Hungary.

Chaos (Woodbury, N.Y.)
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We developed an autocatalytic reaction network exhibiting bistability and pH oscillations. This system demonstrates sustained chemical dynamics near physiological conditions through pH-dependent imine hydrolysis and autocatalyst removal.

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Area of Science:

  • Chemical kinetics
  • Systems chemistry
  • Biochemistry

Background:

  • Autocatalytic networks are fundamental to understanding life's origins.
  • Bistability and oscillations are key features of complex chemical systems.
  • Imine hydrolysis offers a versatile platform for studying reaction dynamics.

Purpose of the Study:

  • To construct and investigate an autocatalytic reaction network based on imine hydrolysis.
  • To explore the emergence of bistability and sustained pH oscillations in an open system.
  • To characterize the dynamic behaviors and bifurcations within the network.

Main Methods:

  • Building an autocatalytic reaction network utilizing imine hydrolysis.
  • Implementing a first-order removal of the autocatalyst.
  • Conducting a systematic parameter search to analyze dynamics and bifurcations.

Main Results:

  • Demonstrated bistability in an open system driven by positive feedback.
  • Achieved sustained pH oscillations near physiological conditions via autocatalyst removal.
  • Observed stoichiometric imine-to-amine conversion coupled with pH oscillations.

Conclusions:

  • The imine hydrolysis network effectively generates complex chemical dynamics, including bistability and oscillations.
  • The system's behavior is tunable through parameter variations, offering insights into chemical evolution.
  • This work provides a model for studying self-organization in chemical systems.