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Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

15
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
15
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

20
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
20
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

14
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
14
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

13
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
13
Urinary Tract Calculi I: Introduction01:28

Urinary Tract Calculi I: Introduction

16
Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
16

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Related Experiment Video

Updated: Jul 15, 2025

Transtubular Endoscopic Posterolateral Decompression for L5-S1 Lumbar Lateral Disc Herniation
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Alkaptonuria Presenting With Lumbar Disc Herniation: A Case Report.

M L Bansal1, Fazal Rehman T1, Amlan Singh1

  • 1Department of Spine Services, Indian Spinal Injuries Centre, New Delhi, IND.

Cureus
|October 3, 2023
PubMed
Summary

Alkaptonuria, a rare genetic disorder, can cause symptomatic lumbar disc herniation. This case highlights diagnosing alkaptonuria by identifying a "black disc" during surgery for back pain.

Area of Science:

  • Genetics
  • Orthopedics
  • Metabolic Disorders

Background:

  • Alkaptonuria (AKU) is a rare autosomal recessive metabolic disorder characterized by ochronosis and increased risk of degenerative joint disease.
Keywords:
alkaptonuriablack discdisc prolapseochronosisspine

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  • Symptomatic lumbar disc herniation requiring surgery is an uncommon manifestation of AKU.