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Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

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Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
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Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

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The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
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Venous Thrombosis III: Interprofessional Care01:29

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Venous Thrombosis IV: Nursing Management01:30

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Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
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Functions of Thyroid Hormones01:18

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
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Thyroid Dysfunction in Patients with and Without Venous Thromboembolism: a Case Control Study.

Rizwana Naushad1, Jayachandran Selvaraj1, Jayaprakash Sahoo2

  • 1Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion
|October 3, 2023
PubMed
Summary

Thyroid dysfunction, including subclinical hypothyroidism, is a significant risk factor for unprovoked venous thromboembolism (VTE). This finding has implications for managing VTE in populations with high thyroid disease prevalence.

Keywords:
Deep vein thrombosisSubclinical hypothyroidismThyroid dysfunctionVenous thromboembolism

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Area of Science:

  • Endocrinology
  • Hematology
  • Internal Medicine

Background:

  • Thyroid dysfunction is common, particularly in India.
  • Recent research suggests a link between thyroid disorders and venous thromboembolism (VTE).
  • Understanding this association is crucial for VTE risk assessment and management.

Purpose of the Study:

  • To investigate whether thyroid dysfunction is a risk factor for unprovoked VTE.
  • To compare thyroid function and antibody profiles in patients with unprovoked VTE and healthy controls.

Main Methods:

  • A case-control study involving 102 patients with unprovoked VTE and 102 matched controls.
  • Assessment of clinical profiles, thyroid function tests (Free T3, Free T4, TSH), and thyroid antibody profiles (Anti TPO, Anti TG).

Main Results:

  • Thyroid disease was significantly more prevalent in the unprovoked VTE group (33.1%) compared to controls (13.7%).
  • Subclinical hypothyroidism (SCH) was also more common in VTE patients.
  • Thyroid dysfunction showed a strong association with unprovoked VTE (OR=3.14), as did SCH (OR=3.71).

Conclusions:

  • Thyroid dysfunction is significantly associated with unprovoked VTE.
  • Subclinical hypothyroidism is identified as a risk factor for unprovoked VTE.
  • These findings highlight the importance of considering thyroid status in VTE risk evaluation.