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Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
Published on: October 4, 2019
Interaction among long non-coding RNA, micro-RNA and mRNA in glioma
Yang Chai1, Shun Liu1, Ming-Xiang Xie1
1Department of Neurosurgery Affiliated Hospital of Zunyi Medical University Zunyi Guizhou China.
Abstract:
With the rapid development and wide application of gene sequencing, biotechnology, and informatics about cancer, it has been found that the main causes of malignant gliomas occurrence not only consist of abnormal mutations of protein-coding genes but also abnormal expressions of non-coding RNA (ncRNA). In this review, we summarize the interaction and mechanism between lncRNA-miRNA-mRNA and gliomas in occurrence, development, aggression, and migration in depth.
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MicroRNAs
lncRNA - Long Non-coding RNAs

