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Calcium carbonate as a phosphate binder in hemodialysis patients
ASAIO Transactions
|July 1, 1986
Insights
Calcium carbonate is as effective as aluminum hydroxide for binding dietary phosphorus in hemodialysis patients. Long-term safety is acceptable with current therapeutic options.
Area of Science:
- Nephrology
- Internal Medicine
- Pharmacology
Background:
- Patients undergoing hemodialysis often experience hyperphosphatemia.
- Dietary phosphorus binders are crucial for managing mineral and bone disorders in these patients.
Purpose of the Study:
- To compare the efficacy and safety of calcium carbonate versus aluminum hydroxide in binding dietary phosphorus.
- To evaluate the long-term safety profile of calcium carbonate in hemodialysis patients.
Main Methods:
- A comparative study assessing phosphorus binding efficacy.
- Evaluation of long-term safety data in a hemodialysis population.
Main Results:
- Calcium carbonate demonstrated comparable efficacy to aluminum hydroxide in binding dietary phosphorus.
- The long-term safety of calcium carbonate was found to be acceptable.
Conclusions:
- Calcium carbonate is a viable and effective alternative to aluminum hydroxide for phosphorus management in hemodialysis.
- Current therapeutic options support the acceptable long-term safety of calcium carbonate in this patient group.
Abstract:
Calcium carbonate appears to be as effective as aluminum hydroxide in binding dietary phosphorus in hemodialysis patients. The long-term safety of this medication appears acceptable in view of today's therapeutic options.