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Concurrent Medication Adherence in Hypertensive Patients With High-Risk Comorbidities
The Journal of Cardiovascular Nursing
|October 3, 2023
Summary
Patients with hypertension and multiple comorbidities face challenges with medication adherence. The study found an inconsistent relationship between the number of high-risk comorbidities and adherence levels.
Area of Science:
- Clinical Pharmacy
- Health Services Research
- Chronic Disease Management
Background:
- Hypertension management often involves multiple medications due to high-risk comorbidities.
- Polypharmacy in patients with hypertension and comorbidities can increase the burden of medication adherence.
- The number of chronic conditions is a potential factor influencing medication adherence.
Purpose of the Study:
- To compare characteristics of patients with hypertension and high-risk comorbidities based on medication adherence.
- To investigate the association between the number of high-risk comorbidities and concurrent medication adherence.
- To identify patterns in medication adherence among patients requiring multiple medications.
Main Methods:
- Secondary data analysis of the 2018 Korea Health Panel Survey.
- Inclusion of 2230 patients with hypertension and at least one high-risk comorbidity on multiple medications.
- Classification into adherent, suboptimal, and nonadherent groups based on medication adherence for each condition, analyzed using multinomial logistic regression.
Main Results:
- The adherent, suboptimal, and nonadherent groups comprised 85%, 11%, and 4% of patients, respectively.
- More high-risk comorbidities were linked to the suboptimal adherence group (aOR=1.46) versus the adherent group.
- Fewer high-risk comorbidities were linked to the nonadherent group (aOR=0.52) versus the adherent group.
Conclusions:
- Three distinct concurrent medication adherence groups were identified.
- The association between the number of high-risk comorbidities and medication adherence groups was inconsistent.
- Further research is needed to understand complex adherence patterns in this patient population.
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