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Genetic Screens

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...

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Related Experiment Video

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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

MG2C: a user-friendly online tool for drawing genetic maps.

Jiangtao Chao^1,2, Zhiyuan Li^3,4, Yuhe Sun³

¹Key Laboratory for Tobacco Gene Resources, Tobacco Research Institute of Chinese Academy of Agricultural Sciences, Qingdao, 266101, China. chaojiangtao@caas.cn.

Molecular Horticulture

|October 3, 2023

Summary

MG2C is a new, user-friendly online tool that simplifies genetic map creation. Researchers can generate standard genetic maps without coding, saving time and effort.

Keywords:

Genetic map MG2C Online tool Perl

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Area of Science:

Genetics
Bioinformatics

Background:

Traditional genetic mapping software requires coding expertise, posing a barrier for many researchers.
Genetic maps are crucial for understanding chromosome structure and facilitating genetic analysis.

Discussion:

MG2C offers a web-based solution for generating genetic maps, requiring only gene locations and chromosome length as input.
The tool utilizes PERL and SVG, featuring a user-friendly interface with adjustable parameters across 8 modules.
Generated maps are in SVG format, allowing for further modification with standard image processing software.

Key Insights:

MG2C eliminates the need for programming skills in genetic map creation.
The online tool streamlines the process, making genetic mapping more accessible.
It provides a time-saving and convenient alternative for researchers without coding backgrounds.

Outlook:

MG2C has been operational since 2015 and updated to version 2.1, demonstrating its stability and continued development.
The tool significantly lowers technical barriers, promoting wider adoption of genetic mapping techniques.
Future updates could potentially expand its functionality or integration with other bioinformatics tools.