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Related Concept Videos

Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

33
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
33
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

37
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
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Updated: Jul 15, 2025

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
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3D Printed Materials for Combating Antimicrobial Resistance.

Mert Tunca Doganay1, Cyril John Chelliah1, Abdullah Tozluyurt1

  • 1Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

Materials Today (Kidlington, England)
|October 4, 2023
PubMed
Summary
This summary is machine-generated.

Three-dimensional (3D) printing offers innovative solutions for antimicrobial resistance (AMR). This technology models complex infections and aids in developing new antibiotic treatments and delivery methods.

Keywords:
3D printingantibioticantibiotic deliveryantibiotic testingantimicrobial resistancebacteriabioprinting

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Area of Science:

  • Biomedical Engineering
  • Microbiology
  • Materials Science

Background:

  • Three-dimensional (3D) printing is a rapidly advancing technology with significant potential in biology and medicine.
  • 3D-printed materials are being explored as alternatives for managing antimicrobial resistance (AMR).

Purpose of the Study:

  • To provide an overview of 3D-printed materials and biosystems for biomedical applications.
  • To highlight the role of 3D printing in addressing the challenge of AMR.

Main Methods:

  • Reviewing recent applications of 3D printing in combating AMR.
  • Discussing the use of 3D printing for modeling microbial environments and host-pathogen interactions.
  • Exploring the application of 3D-printed materials for antibiotic testing and delivery.

Main Results:

  • 3D printing enables precise control over cellular microenvironments, simulating in vivo conditions.
  • 3D printing facilitates the modeling of microbial resistance development.
  • Developed bioprinted systems show promise for targeted bacterial infections and antibiotic testing.

Conclusions:

  • 3D printing technology is crucial for advancing the modeling and treatment of infections.
  • 3D printing offers novel strategies to combat the growing threat of AMR.
  • Bioprinted systems and 3D-printed materials are key innovations for future antimicrobial therapies.