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Hydrogel Cross-Linking via Thiol-Reactive Pyridazinediones

Calise Bahou1, Richard J Spears1, Angela M Ramírez Rosales2,3

  • 1Department of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ, U.K.

Biomacromolecules
|October 4, 2023
PubMed
Summary

Pyridazinediones offer a new way to create pH-sensitive, chemically cross-linked hydrogels with tunable properties. These novel cross-linking agents enable controlled gelation, degradation, and support cell proliferation for biomedical applications.

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