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Effects of Exercise during Chemo- or Radiotherapy on Immune Markers: A Systematic Review
Anne M S de Hoop1,2,3, Karin Valkenet1,2, Jaap J Dronkers2
1Department of Rehabilitation, Physiotherapy Science & Sport, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Oncology
|October 4, 2023
Summary
Regular exercise during cancer treatment shows promising results, positively impacting immune markers without negative effects. Further research will clarify optimal exercise strategies for cancer patients.
Area of Science:
- Immunology
- Oncology
- Exercise Science
Background:
- Cancer patients undergoing radio- or chemotherapy experience immunological stress.
- Chronic regular exercise benefits the immune system, but overload can be detrimental.
- Current exercise recommendations for cancer patients lack detailed evidence on immune marker effects during treatment.
Conclusions:
- Exercise interventions demonstrated promising, generally positive effects on specific immune markers in cancer patients.
- Exercise did not negatively impact immune markers and may offer clinical benefits through suppressed inflammation.
- Future research should establish consensus on key exercise-responsive immune markers and investigate differential effects of training types and intensities.
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