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Stages in human brain development.

H T Epstein

    Brain Research
    |November 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Human brain growth shows significant rate increases around ages 7, 11-12, and 15 years, with earlier data suggesting peaks at 11 and 15 years. These developmental stages are crucial for brain function exploration.

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    Area of Science:

    • Neuroscience
    • Human Growth and Development
    • Developmental Biology

    Background:

    • Human brain and head growth exhibit distinct developmental phases.
    • Previous studies indicated significant growth rate peaks around ages 11 and 15 years.
    • Variations in growth patterns across different datasets necessitate further investigation.

    Purpose of the Study:

    • To identify statistically significant peaks in human brain growth rates.
    • To correlate findings across multiple data sources, including head circumference, cortical thickness, and EEG.
    • To explore the developmental significance of identified growth stages.

    Main Methods:

    • Analysis of a 1974 survey of human brain and head growth data.
    • Examination of extensive head circumference data from multiple countries.

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  • Cross-validation with data on cortical thickness, neuronal arbors, and alpha-frequency EEG energy.

    • Main Results:

    • Statistically significant peaks in brain growth rates identified around ages 7, 11-12, and 15 years.
    • Earlier studies reported peaks at 11 and 15 years, with troughs at intermediate ages (5, 9, 13).
    • Recent data confirm peaks at 7, 12, and 15 years, supported by cortical thickness and EEG data.

    Conclusions:

    • Human brain development features significant growth spurts around ages 7, 11-12, and 15 years.
    • The 15-year peak is currently confirmed primarily in males.
    • The functional implications of these developmental stages are an active area of research.