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Updated: Jul 15, 2025

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Published on: February 5, 2021
Cardiogenic shock in pregnancy
Orene Y O Greer1,2, Rathai Anandanadesan3,4, Nishel M Shah1,2
1Division of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.
Cardiac disease affects 1-4% of pregnancies, with cardiogenic shock (CS) posing a severe risk. Early recognition and management, including mechanical circulatory support (MCS), are crucial for improving outcomes in pregnant women with heart conditions.
Area of Science:
- Cardiology
- Maternal-Fetal Medicine
- Critical Care Medicine
Background:
- Cardiac disease complicates 1%-4% of pregnancies worldwide, particularly in low and middle-income countries (LMICs).
- Rising maternal age, obesity, and comorbidities like pre-eclampsia contribute to acquired cardiovascular disease in pregnancy.
- Increased survival rates for congenital heart disease (CHD) mean more women with CHD are becoming pregnant.
Purpose of the Study:
- To review recent advancements in the classification of cardiogenic shock (CS).
- To explore adaptations of CS classification for improved outcomes in pregnant women.
- To highlight the importance of early recognition and management of cardiac disease during pregnancy.
Main Methods:
- Narrative review of recent developments in cardiogenic shock classification.
- Analysis of how CS classifications can be applied to pregnant populations.
- Discussion of management strategies including mechanical circulatory support (MCS).
Main Results:
- Cardiogenic shock (CS) in pregnancy is associated with significant mortality and morbidity.
- Effective management hinges on early recognition and intervention for reversible causes.
- Individualized care plans and adherence to guidelines have improved clinical outcomes.
Conclusions:
- Adapting current CS classifications may enhance the management of pregnant women at risk.
- Prompt diagnosis and timely intervention are critical for mitigating the risks of CS in pregnancy.
- Further research into tailored CS management strategies for pregnant individuals is warranted.
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