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Personalizing medicine in Africa: current state, progress and challenges.

Paul Owolabi1,2, Yagoub Adam3, Ezekiel Adebiyi1,2,3,4

  • 1Covenant Applied Informatics and Communication, Africa Centre of Excellence (CApIC-ACE), Covenant University, Ota, Ogun State, Nigeria.

Frontiers in Genetics
|October 5, 2023
PubMed
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Personalized medicine offers tailored health interventions, but its adoption in Africa faces challenges despite the continent's genetic diversity. This review examines progress and hurdles for personalized medicine in Africa.

Keywords:
Africagenomicsindividualized medicinepersonalized medicineprecision medicine

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Area of Science:

  • Genomics and Public Health
  • Translational Medicine

Background:

  • Personalized medicine leverages genetics and environment for tailored health interventions.
  • Global adoption faces translation challenges.
  • African populations exhibit significant genetic diversity, necessitating tailored approaches.

Purpose of the Study:

  • To review the current status of personalized medicine adoption in Africa.
  • To identify progress and challenges in implementing personalized medicine across African health systems.
  • To provide insights for stakeholders on deploying personalized medicine effectively in Africa.

Main Methods:

  • Literature review of current research and initiatives on personalized medicine in Africa.
  • Analysis of factors influencing the translation of personalized medicine into clinical practice.
  • Synthesis of challenges and opportunities specific to the African context.

Main Results:

  • Personalized medicine holds promise for addressing diverse African health issues.
  • Significant genetic diversity in African populations requires specific considerations.
  • Barriers to adoption include infrastructure, data, and policy.

Conclusions:

  • Personalized medicine adoption in Africa is crucial for tackling region-specific health challenges.
  • Overcoming implementation barriers is essential for realizing the benefits of personalized medicine.
  • Strategic approaches are needed to deploy personalized medicine effectively across African health systems.