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Prevalence of depression among Iranian children and adolescents: An updated systematic review and meta-analysis
Maedeh Bazargan1, Akram Dehghani1, Mohammad Arash Ramezani2
1Department of Psychology, Najafabad Branch Islamic Azad University Najafabad Iran.
Insights
The pooled prevalence of depression in Iranian children and adolescents is 33.3%. This highlights the urgent need for effective prevention strategies to address this significant mental health concern in the youth population.
Area of Science:
- Pediatric Mental Health
- Epidemiology
- Psychiatry
Background:
- Depression is a prevalent mental disorder in children and adolescents.
- Existing studies show high depression rates in Iran, necessitating pooled analysis for generalizability.
- A systematic review and meta-analysis are crucial for accurate prevalence estimation.
Purpose of the Study:
- To determine the pooled prevalence of depression among Iranian children and adolescents.
- To update existing epidemiological data on youth depression in Iran.
- To provide a comprehensive overview of depression prevalence through systematic review and meta-analysis.
Main Methods:
- A random-effects model was employed to estimate the pooled prevalence of depression.
- Univariate meta-regression was used to analyze factors contributing to heterogeneity.
- Publication bias was assessed using Beggs and Eggers tests and funnel plots.
Main Results:
- The overall pooled prevalence of depression was found to be 33.3% (95% CI: 27.3-39.2).
- Prevalence varied significantly by assessment tool, ranging from 9.0% (K-SADS-PL) to 57.1% (Beak questionnaire).
- Females exhibited higher depression rates (47.2%) compared to males (30.5%), with the highest prevalence in the central region (41.7%).
Conclusions:
- The high prevalence of depression in Iranian youth underscores the critical need for targeted prevention programs.
- Public health initiatives should focus on early detection and intervention for childhood and adolescent depression.
- Further research may explore specific risk factors and effective interventions within diverse geographical regions of Iran.
Background And Aims:
One of the most common mental disorders among children and adolescent is depression. Some of the conducted studies indicate a too-high prevalence of depression, which cannot be generalized to the entire country. So the pooled estimation of the results of different studies is very important to reach valid results. So the current study aimed to determine the prevalence of depression among Iranian children and adolescents using an updated systematic review and meta-analysis.
Methods:
A random-effects model was used to estimate the pooled prevalence of depression (I 2 = 99.7% and Cochran's Q, p < 0.001). To assess the effect of different factors on heterogeneity, the univariate meta-regression model was used. Publication bias was evaluated by Beggs and Eggers tests as well as funnel plots. Data were analyzed by STATA v 11 (StataCorp.). The significance level of the tests was considered less than 0.05.
Results:
The prevalence of depression was 33.3% (95% CI: 27.3-39.2). The most prevalence estimated using the Beak questionnaire (57.1% [95% CI: 50.2-64.0]) and the lowest was estimated using the K-SADS-PL (9.0% [95% CI: 4.0-13.6]). This estimate among females was more than among males (47.2% [95% CI: 35.4-58.9] vs. 30.5 [95% CI: 7.4-53.6]). Regarding the geographical region, the most and the lowest amount of depression was seen in the central with 41.7% (95% CI: 19.2-64.3) and southern region with 21.9% (95% CI: 14.2-29.6), respectively.
Conclusion:
The high prevalence of depressive disorders in Iranian children emphasizes the importance of prevention measures for these disorders.
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