Glycemic control and its associated factors among diabetic heart failure outpatients at two major hospitals in Jordan

Anan S Jarab1,2, Walid A Al-Qerem3, Hanan Hamam1

  • 1Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.

Plos One
|October 5, 2023
PubMed

Insights

Patients with heart failure and type 2 diabetes often have uncontrolled blood glucose. Poor medication adherence and high white blood cell counts are linked to poor glycemic control in these patients.

Area of Science:

  • Cardiology
  • Endocrinology
  • Clinical Medicine

Background:

  • Patients with heart failure (HF) face elevated risks for type 2 diabetes and glycemic dysregulation.
  • The prevalence of uncontrolled blood glucose in HF patients remains largely uncharacterized.
  • Identifying factors linked to poor glycemic control is crucial for developing targeted interventions.

Purpose of the Study:

  • To investigate factors associated with glycemic control in patients diagnosed with both heart failure and type 2 diabetes.
  • To provide preliminary data for the development of effective intervention strategies.

Main Methods:

  • A cross-sectional study was conducted across two major hospitals.
  • Data collection included sociodemographic information, medical records, and a validated questionnaire assessing medication adherence.
  • Regression analysis was employed to identify significant associations.

Main Results:

  • Poor medication adherence was significantly associated with poorer glycemic control (OR = 0.432; 95% CI 0.204-0.912; P<0.05).
  • Elevated white blood cell (WBC) counts were also linked to poor glycemic control (OR = 1.12; 95% CI 1.033-1.213; P<0.01).

Conclusions:

  • Intervention programs aimed at improving blood glucose control in HF patients with diabetes should address medication adherence.
  • Targeting patients with elevated WBC counts may be beneficial for enhancing glycemic management.

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